Four ingredients.
One nightly cream.

A physician-prescribed cream with four actives — GHK-Cu 3%, tretinoin 0.01%, niacinamide 4%, and caffeine 1% — compounded fresh by a licensed U.S. pharmacy and prescribed after a quick online consultation.

Nexxana is a brand operated by Omni Health Ventures Inc., a health and wellness marketing company. We are not a pharmacy, medical practice, or healthcare provider. We connect clients with independent licensed providers and licensed compounding pharmacies — we do not prescribe, compound, or dispense medications.

It contains tretinoin — a prescription retinoid far stronger than OTC retinol — plus a copper peptide at 3%. Neither is something an over-the-counter product can legally match.

It's a copper peptide your body makes less of as you age. At prescription strength it has been shown in clinical studies to support collagen and elastin synthesis, with one trial showing an average 28% increase in collagen density over 3 months.

Yes, but keep your routine simple. Apply Cashmere to clean skin at night. In the morning, use a gentle moisturizer and SPF 30+. Avoid using other exfoliating acids (AHAs, BHAs, benzoyl peroxide), products containing sulfur, resorcinol, or salicylic acid, or additional retinoids at the same time — they may increase irritation. Mention any prescription topicals in your intake so your provider has the full picture.

Most women notice smoother texture within 4 weeks and more visible improvements in tone, firmness, and fine lines by 8–12 weeks. Results build with consistent nightly use. Individual timelines vary.

Each shipment contains up to 3 jars (30g each — one month supply per jar). Your 3-month plan ships in one box, a 6-month plan ships in two boxes (every 3 months), and a 12-month plan ships in four boxes (every 3 months).

Store at room temperature, away from direct sunlight. Some pharmacies recommend refrigeration to extend potency — your prescription will include specific storage instructions.

Most states only require a simple online intake — no video visit needed. Your provider will review your information and, if appropriate, send your prescription directly to the pharmacy. However, if you're located in AR, KS, MS, NJ, NM, RI, WV, or DC, a short video visit with a licensed provider is required. You'll receive a link to schedule it after completing your intake.

Yes — it contains tretinoin. A licensed U.S. clinician reviews your health history before prescribing.

Tretinoin can cause initial dryness, mild peeling, or redness for 2–4 weeks; the niacinamide may help reduce it. Start every other night if your skin is sensitive, then build to nightly. Always use SPF during the day.

No. Tretinoin is not safe during pregnancy or breastfeeding. Your clinician will discuss this during your consultation.

Cashmere is not appropriate for anyone who is pregnant or breastfeeding, has eczema or severely irritated skin in the treatment area, has a known allergy or hypersensitivity to tretinoin or any of the active ingredients, or is under 18. Your provider reviews your full health history before prescribing and will confirm whether Cashmere is appropriate for you.

Yes — SPF 30 or higher every morning is non-negotiable while using any tretinoin product. Tretinoin increases your skin's sensitivity to UV, so daily sun protection is essential for both safety and results.

On 6 and 12-month plans, your physician does a simple follow-up every 3 months to review your progress. On 3-month plans, your initial consultation covers you for the full term.

From $165/month on the 12-month plan, $179 on 6-month, or $199 on 3-month. Every plan includes the cream, physician consultation, free shipping, and ongoing support. HSA/FSA eligible.

In plain packaging from a licensed U.S. compounding pharmacy. Free standard shipping, no cold pack needed.

Plans are billed in full at checkout. Contact support before your order ships if you have questions about your plan.

Cashmere ships to all 50 U.S. states. A licensed compounding pharmacy ships your supply in plain packaging with free standard shipping.

If the reviewing physician determines Cashmere isn't appropriate based on your intake, you won't be charged for the prescription. The consultation is designed to ensure your safety comes first.

You can cancel within 48 hours of ordering for a full refund. After that, because this is a personalized compounded medication, it can't be refunded. You can cancel future renewals anytime. This is disclosed clearly at checkout.

At the end of your plan term, a renewal is initiated to ensure there's no gap in your treatment. You'll be notified before renewal and can cancel at any time before the next term is charged.

Compounded prescriptions are generally not covered by insurance. However, Cashmere is HSA/FSA eligible, so you can use pre-tax health savings to pay.